XVIII.—On nitro-compounds. (Part. I)

Directionality of π-holes in nitro compounds.

A statistical survey of the Cambridge Structural Database reveals that the interaction between the π-holes of nitro groups and electron-rich atoms is somewhat directional. High-level ab initio computations indicate energies up to -6.6 kcal mol(-1).

Anticancer Natural Compounds: Molecular Mechanisms and Functions. Part I

QSAR model for female rat carcinogenicity (TD50) of nitro compounds

2.1.Date of QMRF: 21.08.2009 2.2.QMRF author(s) and contact details: [1]Indrek Tulp Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [2]Tarmo Tamm Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [3]Gunnar Karelson Molcode Ltd. Turu 2, Tartu, 51014, Estonia [email protected] http://www.molcode.com [4]Dimitar Dobchev Molcod...

Antimicrobial activity of a series of halo-nitro compounds.

Sec-alpha-halo-nitro compounds are active antibacterial and antifungal agents, and the sec-bromo derivatives are the most active and stable.

One-pot efficient reductive acetylation of aromatic nitro compounds

An efficient one-pot reductive acetylation of aromatic nitro compounds is developed without isolating the intermediate amine. The nitro compound is efficiently reduced by sodium borohydride and catalytic amount of Pd-C in MeOH-water media in presence / absence of alkali, and the amine thus generated is acetylated by acetic anhydride in situ in excellent yields through easy work-up. The techniqu...